So, that's a one time call and not a recurring event? IMHO that shouldn't be a problem, is it? I'm sorry for not understanding your issue, but it is really not clear what exactly the issue is. Maybe if you describe what it is you are doing on the OnChange event it becomes clear to me what the problem is. Typically, you would do something as an automatic save or a parsing of the contents and if this happens at the start of the application you probably haven't set the content yet, so there shouldn't be a problem.
Again, sorry for my questions, but I'm a bit lost.
Bye,
Bart